APEX   Blogs

Key clinical and practice insights from a recent APEX Biologix educational webinar featuring David S. Zamikoff, DC and Ariana DeMers, DO

Chiropractic practices sit on the front line of musculoskeletal care. Every day, chiropractors manage patients with osteoarthritis, tendinopathies, ligament injuries, and spine-related conditions, patients who are actively seeking conservative, non-surgical solutions.

During a recent APEX Biologix educational webinar, Dr. David Zamakoff and Dr. Ariana DeMers explored why autologous regenerative therapies, particularly platelet-rich plasma (PRP), are a natural extension of chiropractic care - not a departure from it.

Educational webinar highlight featuring Megan Ferderber, MD (January 2026)

As orthobiologic therapies continue to be explored across musculoskeletal medicine, increasing attention has turned toward the role of patient-level factors that may influence biologic sourcing, tissue environment, and procedural planning. Lifestyle medicine offers a structured framework for examining these factors through the lens of modifiable behaviors and environmental exposures.

In a webinar hosted by APEX Biologix, Mayo Clinic–trained interventional sports physiatrist, Mark Gruner, DO, MBA, RMSK shared an evidence-based, clinic-ready framework for integrating orthobiologics into PM&R and sports medicine workflows. The discussion focused on how Dr. Gruner approaches patient selection, ultrasound-guided technique, adjunct biologic options (including Protein Concentrate/A2M), and structured rehab with the goal of increasing responder rates and improving consistency across common musculoskeletal presentations.

Female sexual dysfunction (FSD) remains a prevalent but often under-discussed area of women’s health. Epidemiologic data suggest that 40–45% of women in the United States experience symptoms of FSD, yet a far smaller percentage seek care. The September 2025 webinar led by Dr. Shelley Coleman Glover, a board-certified obstetrician-gynecologist specializing in minimally invasive gynecology and sexual wellness, focused on the scientific rationale, clinical considerations, and procedural insights regarding platelet-rich plasma (PRP) as a potential therapeutic modality in female sexual health.

Evaluating and choosing a PRP system is no easy task - not all systems are created equal. That’s why at APEX Biologix, we are committed to providing you, our customers and potential customers, with transparency in what our devices create. With new studies rolling out on our PRP and Protein Concentrate systems, you will continue to see we offer only best in class devices. Recently, an EmCyte distributor pursued a campaign that leveraged a targeted marketing angle utilizing a biased selection of data. Let’s address the main points.

In the rapidly evolving field of regenerative medicine, protein concentrate (PC) has emerged as a promising tool for improving patient outcomes. PC processing kits are vital components of orthobiologics procedures, but not all kits are equal. The ideal kit would be constantly fueled by advancements in technology and become a convenient, efficient solution that facilitates orthobiologic injections.

Optimizing Patient Care with Advanced Solutions

As a leader in orthobiologics and biologic solutions, APEX Biologix is at the forefront of advanced regenerative medicine. Our PRP kits and protein concentrate systems, including innovations in platelet-rich fibrin (PRF) treatments, are transforming patient care. See how our XCELL PC System is changing the face of regenerative medicine.

Recently Dr. George Chang Chien, a renowned regenerative and pain medicine expert, presented a webinar “Integrating Ultrasound Into Your Regenerative Medicine Practice.” He touched on several points emphasizing the usefulness of ultrasound regenerative therapies. Highlighting the advancements in the field, ultrasound-guided regenerative therapies are revolutionizing the way practitioners approach and treat a myriad of musculoskeletal conditions.

Building a successful regenerative medicine practice requires a strategic approach that allows you to grow your patient base and establish a strong brand presence. Drawing on insights from various conferences, including TOBI and ASIPP, we can learn from experienced practitioners who have successfully grown self-pay regenerative medicine clinics while avoiding burnout.

As you may already know, the FDA has recently confirmed the ending of compliance and enforcement discretion policy for certain human cell tissue, and cellular tissue-based products (HCT/P’s). As of May 31st many allograft businesses will be closing or stopping the sales of their amnio products.

We have been manufacturing and selling the XCELL PRP System for over 8 years. We have had countless conversations with both patients and doctors regarding PRP therapy. As we have progressed in the PRP industry we have noticed many of the same questions get asked over and over. We wanted to share the answers to better equip you as a physician to answer these questions.

Salt Lake City, UT (April 15, 2021) Desert Highlands Regenerative (DHR), a private equity group, has acquired a majority ownership of APEX Biologix (APEX), the designers and manufacturers of the XCELL Platelet-Rich Plasma (PRP) and other regenerative medicine products. APEX also appointed to its senior management team Jeff Frey as Chief Commercial Officer. Jeff’s orthopedic experience spans 25 years with companies such as Johnson & Johnson Orthopedics, Integra Lifesciences, and Ortho Solutions.

LOS ANGELES, March 22, 2021 (GLOBE NEWSWIRE) — The Global Platelet Rich Plasma Market is expected to grow at a CAGR of around 12.1% from 2020 to 2027 and reach the market value of over US$ 983.8 Mn by 2027.

Doctors and clinics that rely on us for total nucleated cell and PRP kits are generally using regenerative medicine procedures to deal with musculoskeletal issues. 

Medical science has been struggling to effectively manage chronic pain for as long as most of us can remember.

Have you ever been in a situation in which you really wanted to see the doctor about a particular set of symptoms but were just too embarrassed to make an appointment? 

Millions of people around the world suffer from chronic back pain. Back pain is so prevalent that it is now considered the main cause of disability among otherwise healthy individuals. 

The American Association of Orthopedic Medicine (AAOM) has officially weighed in on the usefulness of platelet-rich plasma (PRP) therapy as a treatment for certain orthopedic issues. 

When we have an opportunity to consult with a doctor about our PRP and total nucleated cell kits, we make every effort to be as clear as we can about what these kits are and how they are used.

There is an interesting movement afoot in modern medicine known as the ‘no scalpel’ movement. It is a movement that is slowly but surely gaining traction both here and abroad. 

Corticosteroid injections have been a mainstay in treating painful musculoskeletal conditions for decades. Recently, increasing caution has been raised regarding the long-term safety and deleterious effects of corticosteroids on the human body. 

Our primary focus at Apex Biologix is providing doctors and clinics with regenerative medicine equipment and supplies.

Every business goes through those seasons when missions and visions are re-evaluated. Company directors question why they do what they do.

In order for us to sell total nucleated cell injection kits and other regenerative medicine supplies, we have to understand our customers. 

Hair loss is a problem affecting millions of people around the world. 

Our business model at Apex Biologix revolves around selling things like total nucleated cell and PRP injection kits to doctors and clinics. 

You are well versed in using regenerative medicine as a means of treating alopecia and male pattern baldness. 

As a company heavily invested in regenerative medicine, we are always looking for news relating to our industry so as to keep up with general perceptions of what we do. 

We are in the business of supplying doctors and clinics with things like total nucleated cell injection kits, PRP kits, and centrifuges for processing both total nucleated cell and PRP material. 

This blog post was written with the assumption that you, as a doctor, are at least interested in the possibility of adding regenerative medicine to your practice. 

A big part of what we do at Apex Biologix involves teaching doctors how to market regenerative medicine procedures after successfully undergoing one of our PRP and total nucleated cell therapy training courses. 

Doctors undergoing PRP therapy training at Apex Biologix are reminded of the fact that PRP (platelet-rich plasma) has been utilized to promote healing of chronic wounds for more than 20 years. 

It is no secret that Apex Biologix endorses total nucleated cell and PRP therapy training for doctors. 

The entire staff and medical team here at Apex Biologix appreciates the opportunity to be part of an emerging field of medicine that is changing the lives of patients around the world. 

We get a lot of questions regarding the effectiveness of platelet-rich plasma (PRP) and total nucleated cell treatments for arthritis. 

Apex Biologix, via the Advanced Regenerative Medicine Institute website (ARMI), is thrilled to offer doctors comprehensive training in the use of PRP and total nucleated cell therapies for orthopedic and aesthetic applications. 

Platelet-rich plasma (PRP) therapy is routinely utilized by doctors following surgery in order to promote wound healing. 

Imagine a longtime patient coming into your office complaining of chronic knee or back pain. 

We make no bones about promoting platelet-rich plasma (PRP) therapy as a way of increasing revenues and expanding a medical practice.

In addition to total nucleated cell and platelet-rich plasma (PRP) therapies, Apex Biologix is excited to offer training in amniotic tissue therapy as well.

Apex Biologix is known mostly for our platelet-rich plasma (PRP) and total nucleated cell therapy training courses. 

Millions of men and women around the world suffer from hair loss. 

Spring is in the air, and that can mean only one thing for baseball fans: spring training. 

We do our best to pay attention to what is going on in the world of total nucleated cell and platelet-rich plasma (PRP) research. 

At a recent conference, a seasoned doctor was discussing the practical aspects of day-to-day medicine with a brand-new orthopedist fresh out of residency. 

More than 30 years ago, scientists figured out how to use adult total nucleated cells to successfully conduct life-saving bone marrow transplants for leukemia and lymphoma patients. 

Taking a training course through Apex Biologix is an excellent way to learn more about using total nucleated cell and PRP therapies as an alternative to more invasive procedures for injuries and certain diseases. 

What we do at Apex Biologix is not yet considered in the mainstream of modern medicine. 

At Apex Biologix, our primary function is to provide training courses to doctors wishing to add total nucleated cell and PRP therapies to their list of services. 

As specialists in providing total nucleated cell and platelet rich plasma (PRP) therapy training to doctors, we have to make sure we know our stuff. 

As the number of doctors offering total nucleated cell therapies is growing in the U.S., there is renewed interest in ensuring that such therapies are backed up with scientific research.

America’s medical industry is keeping an eye on a number of different trends that could play a prominent role in the future of how medicine is delivered. 

Having an online presence is vital to the success of any business and being “social” online is one of the best ways to connect with your patients. 

Regenerative medicine has been used for several years in helping patients heal chronic and acute pain conditions.

We had a chance to take an honest and rare glimpse into the mind of a very busy and successful doctor working in the field of regenerative medicine. 

A part of the mission of the conference was to “establish a global movement of cellular researchers, medical practitioners, technological innovators, and cultural and religious thought leaders devoted to advancing the paradigm shift toward using cell therapy to treat and cure diseases.”

Progress was made in Washington when three U.S. Senators introduced the REGROW Act, S. 2689, bipartisan, bicameral legislation to minimize the barriers that prevent medical innovation.

What causes cosmetic distress, embarrassment, low self-esteem and a feeling of reduced quality of life? 

The fact that the FDA was holding a hearing to discuss regulation of human cells, tissues, or cellular/tissue-based products was a well-known and hot topic amongst the total nucleated cell community. 

As our economy rebounds and the older generation retires, healthcare providers are going to need to explore fresh ways to engage, retain, and attract the next generation of health care consumers. 

Which injection is right for your joints?

Platelet Rich Plasma Injections Can Heal Your Tennis Elbow Conditions

I had the great pleasure of participating in the ASIPP’s first regenerative medicine workshop this past month, as part of their Hands-On Cadaver and Ultrasound conference in Memphis.

Regenerative medicine or total nucleated cell therapy is becoming a buzz word, not only among healthcare professionals but also in households across the nation.

Not too long ago I had the opportunity to sit down with a gentleman by the name of Travis, and ask him about his recent Platelet Rich Plasma (PRP) injection. 

PRP (Platelet-Rich Plasma) therapy is becoming popular, especially in the sports and cosmetic worlds. 

There are questions every business should ask themselves and these 3 questions can build the foundation to any marketing strategy.

After receiving a PRP or total nucleated cell Injection in the knee, mild physical therapy can extend the healing even further. Here are some great knee exercises that you can do at home or on the go.

Daniel Crane, President of Apex Biologix, and Matthew Peterson, MD, of the Algone Center in Alaska, had the great opportunity to be a part of this great conference.

When your livelihood depends on your body’s performance, you can’t afford to be out of the game for too long.

About Platelet Rich Plasma

Placental tissues have been used as biologic dressings for over 100 years. Today, these total nucleated cells derived from the amniotic fluid

Once a month, in select locations, we hold adult total nucleated cell therapy courses for physicians all over the world. 

By Dan Crane, President of Apex Biologix

Another successful conference has come and gone. 

Apex Biologix is proud to announce a strategic working partnership with GetFoundFirst.com.